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LEAD HORSE TECHNOLOGIES, INC.

Lead Horse TechnologiesTM (LHT) is a Drug Safety Technology company using Health IT to develop products for other Health IT companies and end-users in support of positive benefit/risk profiles, lower pharmacy costs, and safer drug launches, whether in the clinical trial phase or in the post-marketing environment. We support the practice of personalized medicine and work to reduce the rates, severity, and costs associated with Adverse Drug Reactions (ADRs).

The MedloomTM Decision Support System answers ADR queries using content from multiple data sources, including drug labels, but also pharmacovigilance registries. Besides integrating legacy safety data from drug labels, OTCs, and herbals, the Medloom DSS integrates post-marketing safety data from the US FDA’s MedWatch-populated Adverse Event Reporting System (AERS) database, as well as its own real-time AERS data, which are immediately available to Medloom users anywhere in response to ADR queries.

LHT’s Medical Ontology-Based Search Term Expansion Rationale (MobsterTM) technology allows an ADR query to be made using the term, e.g., liver toxicity, but it actually searches through our myriad data sources with hundreds of related clinical terms using concept maps to clinical ontologies like SNOMED-CT and others. This approach avoids the frustrating results returned when a doctor knows there’s something in a drug label related to a specific problem but can’t find it in a medical reference system if they’re not stating it exactly as written. We also have developed an artificial intelligence system that discovers significant Drug-ADR relationships in pharmacovigilance databases.

LHT’s Association Rule Discovery-Vetted AERS Research Component (ArdvarcTM) is an A.I. system that allows Medloom users to get a handle on important drug-ADR associations in near real-time, whether it’s during a clinical trial or after a drug is launched. The Company began as a Delaware corporation in Aurora, Colorado on April 17, 2006 but relocated to Junction City, Kansas in June of 2007. LHT's U.S. management team consists of experienced science, medicine, technology, and finance personnel. Read more about the Medloom DSS and its embedded drug safety management technologies on our products page.

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